Helicobacter pylori – 2021
نویسندگان
چکیده
Összefoglaló. A Helicobacter pylori továbbra is a világ legelterjedtebb fertőzése: prevalenciája fejlődő országokban 70–80%, fejlett csökkenő tendenciát mutat. dél-magyarországi véradókban prevalencia 32%-ra csökkent. migráció befogadó ország számára fertőzés fokozott kockázatával jár. szövettani diagnózisban az immunhisztokémiai vizsgálat pontosabb hagyományos Giemsa-festésnél. mesterséges intelligencia érzékenysége endoszkópiáéval összehasonlítva 87%, pontossága 86%. Az újgenerációs szekvenálással lehetséges egy biopsziás mintából több antibiotikumérzékenység meghatározása. kezelésének európai regisztere kimutatta, hogy 2013 és 2018 között bizmutalapú négyes vagy 14 napos egyidejű kezelések hatásosabbak, mint hármas kezelés, de elterjedésük igen lassú folyamat, jelentős földrajzi különbségekkel. új típusú koronavírus (SARS-CoV-2) felléphet fertőzésben is, egymás kóros hatását felerősítve. diagnosztikai módszerek korlátozottak. Protonpumpagátlók szedése növeli COVID–19-fertőzés kockázatát annak súlyos kimenetelét. Előzetesen ismert peptikus fekély, vérzés, illetve antikoguláns kezelés előtt eradikáció vírusos lezajlása után indokolt. probiotikumoknak eradikációra gyakorolt hatásáról 20, közepes minőségű metaanalízis született, így konszenzusokban foglalt álláspontok sem egyértelműek: jövőben ezt tisztázni kell. Orv Hetil. 2021; 162(32): 1275–1282. Summary. still the most widespread infection in world: its overall prevalence 70–80% developing regions, but fortunately it decreasing Western world. The blood donors from South-Eastern Hungary decreased 63% 1990’s to 32% 2019. Migration constitutes an increased risk of for destination countries. Immunohistochemistry has proven be more accurate histological diagnosis than conventional Giemsa stain. sensitivity and accuracy artificial intelligence as compared videoendoscopy were 87% 86%, respectively. European Register on management revealed that concomitant quadruple 14-day bismuth-based therapies are efficient triple combinations, although their incorporation practice long-lasting process, with large geographical variations. novel type coronavirus can also occur -infected patients, mutually enhancing pathogenetic effects. Diagnostic possibilities limited this setting. use proton pump inhibitors increases viral severity disease. Eradication treatment seems justified patients previously known peptic ulcers or gastrointestinal bleeding, before starting anticoagulant treatment, must postponed after resolution infection. effect probiotics eradication was addressed by medium-to-low quality meta-analyses so, recommendations guidelines equivocal, which clarified future higher studies.
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متن کاملHelicobacter pylori
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ژورنال
عنوان ژورنال: Orvosi Hetilap
سال: 2021
ISSN: ['1788-6120', '0030-6002']
DOI: https://doi.org/10.1556/650.2021.32181